Role of Ultrasound-Guided Marker Placement in Breast Lesion for Precise Localization, Surgical Resection, Neoadjuvant Chemotherapy Response, and Post-Chemotherapy Follow-Up

Objective To evaluate the effectiveness of ultrasound-guided marker placement in the precise localization of breast lesions, facilitate accurate surgical resection, and monitor tumor response during and after neoadjuvant chemotherapy. Materials and methods From January 2022 to December 2022, 70 female patients with breast carcinoma underwent a trial of metallic marker insertion into the tumor. The markers were made by cutting 5CC disposable syringe needles having a total length of 5 mm. These markers were inserted using a 16 G LP needle having a length of 10 cm. Results Among 70 female breast cancer patients (mean age 47.9 ± 8.0 years), ultrasound-guided metallic markers enabled precise tumor localization before, during, and after neoadjuvant chemotherapy. In 45 patients receiving chemotherapy, tumor size significantly decreased from 3.66 ± 0.69 cm to 0.61 ± 0.21 cm (p < 0.00001). Marker-guided surgery achieved complete tumor excision with negative margins. Intraoperative imaging and postoperative histopathology confirmed accurate localization and successful resection. Conclusion Ultrasound-guided marker placement enables precise tumor localization after neoadjuvant chemotherapy, improving surgical accuracy and breast cancer treatment outcomes.