Role of NR4A1-Caveolin-1 Axis in the Orchestration of Mitophagy During Macrophage Senescence
Overall, our study unraveled The NR4A1-caveolin-1 axis orchestrates mitophagy and inflammation in senescent macrophages, shedding light on AS pathogenesis and suggesting potential therapeutic targets to mitigate macrophage-driven inflammation and oxidative stress.
Authors
- Xiuting Huang
- Tian Tian (ORCID: https://orcid.org/0000-0003-1830-9498)
- Pei Li (ORCID: https://orcid.org/0000-0001-9951-6899)
Institutions
- Beijing Chao-Yang Hospital, Capital Medical University (CN)
- Beijing Shijingshan Hospital (CN)
Publication Details
- Journal
- Cellular Physiology and Biochemistry
- Published
- 2025-08-05
- DOI
- https://doi.org/10.33594/000000796
- Citations
- 2
- Primary Topic
- Nuclear Receptors and Signaling
- Type
- article
- Field-Weighted Citation Impact
- 1.82