Inverse Regulation of <scp>TLR4</scp> and <scp>PD</scp> ‐ <scp>L1</scp> Shapes the Inflammatory Tumor Microenvironment in Oral Squamous Cell Carcinomas
These findings taken together suggest that there is a differential regulation of the immune response coordinated by activation of PD-L1 or TLR4 affecting T cell response.
Authors
- Francesco Longo (ORCID: https://orcid.org/0000-0002-7605-2953)
- Giorgio Mori (ORCID: https://orcid.org/0000-0001-6731-0247)
- Francesco Miele (ORCID: https://orcid.org/0009-0008-7368-258X)
- Camila Alves Ferri (ORCID: https://orcid.org/0000-0003-3421-6443)
- Margherita Cerrone (ORCID: https://orcid.org/0000-0001-7791-6082)
- Raffaele Barile (ORCID: https://orcid.org/0009-0000-1081-7928)
- Monica Cantile (ORCID: https://orcid.org/0000-0001-7840-3369)
- Ilenia Sara De Stefano (ORCID: https://orcid.org/0000-0002-4955-2039)
- Rosanna Zamparese
- Angela Santoro (ORCID: https://orcid.org/0000-0002-6964-5152)
- Vito Rodolico (ORCID: https://orcid.org/0000-0003-1409-4207)
- Giuseppe Pannone (ORCID: https://orcid.org/0000-0003-4198-407X)
- Lorenzo Lo Muzio (ORCID: https://orcid.org/0000-0003-4633-4893)
- Roberta Seccia
- Fernanda Visioli (ORCID: https://orcid.org/0000-0002-4033-8431)
- Gian Franco Zannoni (ORCID: https://orcid.org/0000-0002-4473-7560)
- Giuseppina Campisi (ORCID: https://orcid.org/0000-0002-9443-0495)
- Maria Carmela Pedicillo (ORCID: https://orcid.org/0000-0002-4329-8156)
- Renato Franco (ORCID: https://orcid.org/0000-0002-8340-3184)
- Gabriella Aquino (ORCID: https://orcid.org/0000-0002-8777-6279)
- Francesco Angelillis
- Silvana Papagerakis (ORCID: https://orcid.org/0000-0003-3846-2721)
Institutions
- University of Foggia (IT)
- Universidade Federal do Rio Grande do Sul (BR)
- University of Campania "Luigi Vanvitelli" (IT)
- Agostino Gemelli University Polyclinic (IT)
- University of Campania "Luigi Vanvitelli" (IT)
- Nini Hospital (LB)
- Ospedale Monaldi (IT)
- Istituto Nazionale Tumori IRCCS "Fondazione G. Pascale" (IT)
- Azienda Ospedaliera Universitaria Policlinico "Paolo Giaccone" di Palermo (IT)
- Université Laval (CA)
- University of Palermo (IT)
Publication Details
- Journal
- Journal of Oral Pathology and Medicine
- Published
- 2025-08-05
- DOI
- https://doi.org/10.1111/jop.70012
- Citations
- 1
- Primary Topic
- Cancer Immunotherapy and Biomarkers
- Type
- article
- Field-Weighted Citation Impact
- 1.05
Funders
- Università degli Studi di Foggia
- European Commission