Hypertriglyceridemia as a Key Contributor to Abdominal Aortic Aneurysm Development and Rupture: Insights From Genetic and Experimental Models

These findings identify hypertriglyceridemia as a key contributor to AAA pathogenesis and suggest that targeting TG-rich lipoproteins may be a promising therapeutic strategy for AAA.

Authors

Institutions

Publication Details

Journal
Circulation
Published
2025-08-05
DOI
https://doi.org/10.1161/circulationaha.125.074737
Citations
9
Primary Topic
Aortic aneurysm repair treatments
Type
article
Field-Weighted Citation Impact
13.67
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Hypertriglyceridemia as a Key Contributor to Abdominal Aortic Aneurysm Development and Rupture: Insights From Genetic and Experimental Models

Anna Schwendeman, Y. Eugene Chen, Guizhen Zhao, Ida Surakka et al.
9 citations
Circulation
Aortic aneurysm repair treatments
13.67
article

Hypertriglyceridemia as a Key Contributor to Abdominal Aortic Aneurysm Development and Rupture: Insights From Genetic and Experimental Models

Anna Schwendeman, Y. Eugene Chen, Guizhen Zhao, Ida Surakka, Hong Lü, Yaozhong Liu, Xiaokang Wu, Ryan E. Temel, Yongjie Deng, Hong Yu Liu, Huilun Wang, Haocheng Lu, Alan Daugherty, Lin Chang, Lei Cai, Yanhong Guo, Minzhi Yu, Yang Zhao, Jifeng Zhang, Chao Xue, Ying Zhao, Yalun Cheng
article en
9 citations

Abstract

These findings identify hypertriglyceridemia as a key contributor to AAA pathogenesis and suggest that targeting TG-rich lipoproteins may be a promising therapeutic strategy for AAA.

CirculationVol. 152(12)
University of Kentucky (US), University of Michigan (US), Southern University of Science and Technology (CN), World Wide Web Consortium (US), Rochester General Hospital (US), Michigan Center for Translational Pathology (US), University of Houston (US), University of Virginia (US)
Good health and well-being
Openalex Percentile: Top 1%
Aortic aneurysm repair treatments
13.67
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.