How Much Variance Exists Among Published Definitions of Proximal Junctional Kyphosis? A Retrospective Cohort Study of Adult Spinal Deformity

<b>Background/Objectives</b>: We sought to characterize the variance and overlap among definitions of Proximal Junctional Kyphosis (PJK) used in the adult spinal deformity (ASD) literature. PJK is defined as excess in PJK angle, a Cobb angle between the upper-instrumented vertebra (UIV) and a supra-adjacent vertebra (SAV), either one (UIV+1) or two (UIV+2) levels rostral of the UIV. No expert consensus exists for threshold angle or which SAV to use. <b>Methods</b>: A total of 116 thoracolumbar fusion patients ≥ 65 years old were reviewed. The UIV+1 and UIV+2 angles were measured. Six definitions of PJK from the literature were evaluated. These definitions were selected based on citation frequency, historical relevance, and accessibility through commonly used databases. Pearson's Chi-squared and pairwise comparisons were performed to evaluate the distinctness and agreement rates among these definitions. <b>Results</b>: The six definitions of PJK were as follows: <b>[PJK20]</b> PJK angle ≥ 20° with UIV+2 as the (SAV), <b>[PJK10]</b> PJK angle ≥ 10° with a >10° change from pre-op with UIV+2 as the SAV, <b>[PJK2SD]</b> PJK angle > 2 standard deviations from average with UIV+1 as the SAV, <b>[PJK10+10]</b> PJK angle ≥ 10° with a >10° change from pre-op with UIV+1 as the SAV, <b>[PJK15]</b> PJK angle > 15° with UIV+1 as the SAV, and <b>[PJK30]</b> PJK angle > 30° with UIV+2 as the SAV, or displaced rod fracture, or reoperation within 2 years for junctional failure, pseudoarthrosis, or rod fracture. [PJK10] and <b>[PJK2SD]</b> were the most distinct definitions while <b>[PJK20]</b>, <b>[PJK10+10]</b>, <b>[PJK15]</b>, and <b>[PJK30]</b> showed no significant pairwise differences. [PJK2SD] was stringent, while definition <b>[PJK30]</b> included unique diagnostic information not captured by other definitions. <b>Conclusions</b>: The use of <b>[PJK20]</b>, <b>[PJK10+10]</b>, <b>[PJK15]</b>, or <b>[PJK30]</b> is recommended for consistency, with <b>[PJK15]</b> presenting the best balance. Stringent <b>[PJK2SD]</b> may be beneficial for identifying severe PJK, though with low sensitivity. Overall, PJK definitions must be standardized for the consistent reporting of clinical outcomes and research comparability.

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Journal
Journal of Clinical Medicine
Published
2025-08-04
DOI
https://doi.org/10.3390/jcm14155469
Primary Topic
Scoliosis diagnosis and treatment
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article
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article

How Much Variance Exists Among Published Definitions of Proximal Junctional Kyphosis? A Retrospective Cohort Study of Adult Spinal Deformity

Alexander T. Yahanda, Steven E. Vogl, Tim Bui, Miguel A. Ruiz-Cardozo et al.
Journal of Clinical Medicine
Scoliosis diagnosis and treatment
article

How Much Variance Exists Among Published Definitions of Proximal Junctional Kyphosis? A Retrospective Cohort Study of Adult Spinal Deformity

Alexander T. Yahanda, Steven E. Vogl, Tim Bui, Miguel A. Ruiz-Cardozo, Karan Joseph, Camilo A. Molina
article en

Abstract

<b>Background/Objectives</b>: We sought to characterize the variance and overlap among definitions of Proximal Junctional Kyphosis (PJK) used in the adult spinal deformity (ASD) literature. PJK is defined as excess in PJK angle, a Cobb angle between the upper-instrumented vertebra (UIV) and a supra-adjacent vertebra (SAV), either one (UIV+1) or two (UIV+2) levels rostral of the UIV. No expert consensus exists for threshold angle or which SAV to use. <b>Methods</b>: A total of 116 thoracolumbar fusion patients ≥ 65 years old were reviewed. The UIV+1 and UIV+2 angles were measured. Six definitions of PJK from the literature were evaluated. These definitions were selected based on citation frequency, historical relevance, and accessibility through commonly used databases. Pearson's Chi-squared and pairwise comparisons were performed to evaluate the distinctness and agreement rates among these definitions. <b>Results</b>: The six definitions of PJK were as follows: <b>[PJK20]</b> PJK angle ≥ 20° with UIV+2 as the (SAV), <b>[PJK10]</b> PJK angle ≥ 10° with a >10° change from pre-op with UIV+2 as the SAV, <b>[PJK2SD]</b> PJK angle > 2 standard deviations from average with UIV+1 as the SAV, <b>[PJK10+10]</b> PJK angle ≥ 10° with a >10° change from pre-op with UIV+1 as the SAV, <b>[PJK15]</b> PJK angle > 15° with UIV+1 as the SAV, and <b>[PJK30]</b> PJK angle > 30° with UIV+2 as the SAV, or displaced rod fracture, or reoperation within 2 years for junctional failure, pseudoarthrosis, or rod fracture. [PJK10] and <b>[PJK2SD]</b> were the most distinct definitions while <b>[PJK20]</b>, <b>[PJK10+10]</b>, <b>[PJK15]</b>, and <b>[PJK30]</b> showed no significant pairwise differences. [PJK2SD] was stringent, while definition <b>[PJK30]</b> included unique diagnostic information not captured by other definitions. <b>Conclusions</b>: The use of <b>[PJK20]</b>, <b>[PJK10+10]</b>, <b>[PJK15]</b>, or <b>[PJK30]</b> is recommended for consistency, with <b>[PJK15]</b> presenting the best balance. Stringent <b>[PJK2SD]</b> may be beneficial for identifying severe PJK, though with low sensitivity. Overall, PJK definitions must be standardized for the consistent reporting of clinical outcomes and research comparability.

Journal of Clinical MedicineVol. 14(15)
Washington University in St. Louis (US)
Openalex Percentile: Top 68%
Scoliosis diagnosis and treatment
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