Celastrol treatment attenuates the inflammatory response in Alzheimer’s disease model mice
Taken together, the results indicate that celastrol treatment attenuated the inflammatory response in AD mice by promoting microglial M2 polarization via the TLR4/NFκB pathway.
Authors
- Ping Wang (ORCID: https://orcid.org/0000-0002-2710-7188)
- Fanfan Cao
- Zhong Zheng (ORCID: https://orcid.org/0000-0002-3500-9510)
- Ying Wang (ORCID: https://orcid.org/0000-0003-2121-7025)
- Denghai Zhang
- Limin Xu (ORCID: https://orcid.org/0000-0002-3466-8290)
- Qin Shi (ORCID: https://orcid.org/0000-0002-8694-2685)
- Pan Zhang (ORCID: https://orcid.org/0000-0001-9974-8753)
Institutions
- University of Shanghai for Science and Technology (CN)
- Second Military Medical University (CN)
- Shanghai Pudong New Area Gongli Hospital (CN)
Publication Details
- Journal
- Neurological Research
- Published
- 2025-08-05
- DOI
- https://doi.org/10.1080/01616412.2025.2534077
- Primary Topic
- Neuroinflammation and Neurodegeneration Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00