Safety and efficacy of rotigotine in patients with frontotemporal dementia: a phase 2, double-blind, randomized, placebo-controlled, multicenter trial
This trial was funded by a joint grant from the Alzheimer Drug Discovery Foundation (ADDF) and the Association for Frontotemporal Degeneration (AFTD) grant to GK and BB (GFTD-201902-2017958).
Authors
- Valentina Pezzopane (ORCID: https://orcid.org/0000-0001-8917-9526)
- Caterina Motta (ORCID: https://orcid.org/0000-0001-6734-6979)
- Elias Paolo Casula (ORCID: https://orcid.org/0000-0002-5039-973X)
- Pasquale Romano
- Francesco Di Lorenzo (ORCID: https://orcid.org/0000-0003-4588-4041)
- Sonia Bonnı̀ (ORCID: https://orcid.org/0000-0002-1780-4131)
- Enrico Premi (ORCID: https://orcid.org/0000-0002-4342-6963)
- Michele Maiella (ORCID: https://orcid.org/0000-0003-4017-3769)
- Clarissa Ferrari (ORCID: https://orcid.org/0000-0002-4101-6872)
- Silvia Lucchini (ORCID: https://orcid.org/0000-0003-2161-491X)
- Romina Esposito (ORCID: https://orcid.org/0000-0002-7407-9917)
- Martina Assogna (ORCID: https://orcid.org/0000-0002-8588-1112)
- Emanuele Cerulli Irelli (ORCID: https://orcid.org/0000-0003-3906-555X)
- Luca Battistini (ORCID: https://orcid.org/0000-0002-6488-4891)
- Alessia D’Acunto
- Yasmine Gadola
- Ilaria Borghi (ORCID: https://orcid.org/0000-0002-3058-3337)
- Giacomo Koch (ORCID: https://orcid.org/0000-0001-6155-9439)
- Antonella Alberici (ORCID: https://orcid.org/0000-0001-7137-717X)
- Gisella Guerrera (ORCID: https://orcid.org/0000-0002-3467-6469)
- Francesco Bertagna (ORCID: https://orcid.org/0000-0003-2980-5964)
- Lucia Mencarelli (ORCID: https://orcid.org/0000-0002-4006-4629)
- Barbara Borroni (ORCID: https://orcid.org/0000-0001-9340-9814)
- Valeria Bracca
- Matteo Ferraresi
- Alessandro Martorana (ORCID: https://orcid.org/0000-0002-2489-3304)
- Antonio Daniele
- Francesca Candeo
- Andrea Ludovici
Institutions
- Università Cattolica del Sacro Cuore (IT)
- University of Rome Tor Vergata (IT)
- Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia (IT)
- Centro San Giovanni di Dio Fatebenefratelli (IT)
- Center for Translational Neurophysiology of Speech and Communication (IT)
- Fondazione Poliambulanza Istituto Ospedaliero (IT)
- Fondazione Santa Lucia (IT)
- Libera Università Internazionale degli Studi Sociali Guido Carli (IT)
- University of Brescia (IT)
- Sapienza University of Rome (IT)
Publication Details
- Journal
- The Lancet Regional Health - Europe
- Published
- 2025-08-05
- DOI
- https://doi.org/10.1016/j.lanepe.2025.101409
- Citations
- 2
- Primary Topic
- Neurological Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.68
Funders
- Alzheimer's Drug Discovery Foundation
- BrightFocus Foundation
- Jazz Pharmaceuticals
- European Commission
- Ministero della Salute
- Ministero dell’Istruzione, dell’Università e della Ricerca
- Angelini Pharma