<i>N</i>-(3-Chloro-4-hydroxyphenyl)acetamide

In the title compound, C<sub>8</sub>H<sub>8</sub>ClNO<sub>2</sub>, the acetamide substituent is twisted out of the phenyl plane, forming a dihedral angle of 58.61 (7)°. In the extended structure, each mol-ecule donates two hydrogen bonds [N-H⋯O(carbon-yl) and O-H⋯O(carbon-yl)] and thus also accepts two such hydrogen bonds. The chlorine atom is not involved in the hydrogen bonding.

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Publication Details

Journal
IUCrData
Published
2025-08-04
DOI
https://doi.org/10.1107/s2414314625006959
Citations
1
Primary Topic
Phenothiazines and Benzothiazines Synthesis and Activities
Type
article
Field-Weighted Citation Impact
0.81

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article

N-(3-Chloro-4-hydroxyphenyl)acetamide

Rao M. Uppu, Frank Rolf Fronczek
1 citations
IUCrData
Phenothiazines and Benzothiazines Synthesis and Activities
0.81
article

N-(3-Chloro-4-hydroxyphenyl)acetamide

Rao M. Uppu, Frank Rolf Fronczek
article en
1 citations

Abstract

In the title compound, C<sub>8</sub>H<sub>8</sub>ClNO<sub>2</sub>, the acetamide substituent is twisted out of the phenyl plane, forming a dihedral angle of 58.61 (7)°. In the extended structure, each mol-ecule donates two hydrogen bonds [N-H⋯O(carbon-yl) and O-H⋯O(carbon-yl)] and thus also accepts two such hydrogen bonds. The chlorine atom is not involved in the hydrogen bonding.

IUCrDataVol. 10(8)
Louisiana State University (US), Southern University and Agricultural and Mechanical College (US), Southern University (BD)
National Science Foundation, National Institutes of Health, National Institute of General Medical Sciences, Division of Chemistry
Openalex Percentile: Top 25%
Phenothiazines and Benzothiazines Synthesis and Activities
0.81
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