AIE Active π-Conjugated Dipyridyl-Dipyrroethene for Selective Bioanalyte Recognition

We demonstrated the design and photophysical properties of a dual-state emissive π-conjugated dipyridyl-dipyrroethene chromophore (<b>6</b>) synthesized via selective diformylation of (<i>E</i>)-dipyrroethene followed by condensation with 2-amino pyridine. The rational molecular design, incorporating both hydrogen bonding and π···π interactions, leads to a unique supramolecular architecture in the solid state, and the system exhibits aggregation-induced emission properties. We further extend the applicability of chromophore <b>6</b> for the selective detection of serum albumin.