Evaluation of Short-to-medium Term Efficacy of Guselkumab and Secukinumab in Overweight and Obese Patients with Moderate to Severe Plaque Psoriasis: A 24-Week Single-center Retrospective Study

Guselkumab and Secukinumab demonstrated good short-to-medium-term efficacy in Chinese patients with moderate to severe plaque psoriasis. In patients with a BMI ≥25 kg/m<sup>2</sup>, Secukinumab demonstrated a faster onset of efficacy, while Guselkumab demonstrated significantly higher efficacy at week 24.

Authors

Institutions

Publication Details

Journal
Indian Journal of Dermatology
Published
2025-08-05
DOI
https://doi.org/10.4103/ijd.ijd_663_23
Citations
2
Primary Topic
Psoriasis: Treatment and Pathogenesis
Type
article
Field-Weighted Citation Impact
1.59
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article

Evaluation of Short-to-medium Term Efficacy of Guselkumab and Secukinumab in Overweight and Obese Patients with Moderate to Severe Plaque Psoriasis: A 24-Week Single-center Retrospective Study

Yang Li, Xiuqiu Lin, Min Ou, Yunling Yan et al.
2 citations
Indian Journal of Dermatology
Psoriasis: Treatment and Pathogenesis
1.59
article

Evaluation of Short-to-medium Term Efficacy of Guselkumab and Secukinumab in Overweight and Obese Patients with Moderate to Severe Plaque Psoriasis: A 24-Week Single-center Retrospective Study

Yang Li, Xiuqiu Lin, Min Ou, Yunling Yan, Xiaohua Wang, Junjie Lin
article en
2 citations

Abstract

Guselkumab and Secukinumab demonstrated good short-to-medium-term efficacy in Chinese patients with moderate to severe plaque psoriasis. In patients with a BMI ≥25 kg/m<sup>2</sup>, Secukinumab demonstrated a faster onset of efficacy, while Guselkumab demonstrated significantly higher efficacy at week 24.

Indian Journal of DermatologyVol. 70(5)
Third Affiliated Hospital of Southern Medical University (CN), Shenzhen Chronic Disease Prevention Center (CN), Fuzhou Dermatosis Prevention Hospital (CN), Huizhou Central People's Hospital (CN), Shenzhen Nanshan Center for Chronic Disease Control (CN), Southern Medical University (CN), Huizhou University (CN)
Openalex Percentile: Top 15%
Psoriasis: Treatment and Pathogenesis
1.59
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Evaluation of Short-to-medium Term Efficacy of Guselkumab and Secukinumab in Overweight and Obese Patients with Moderate to Severe Plaque Psoriasis: A 24-Week Single-center Retrospective Study — Yang Li, Xiuqiu Lin, et al. · Indian Journal of Dermatology (2025) | TGRS Research Map | TGRS