Technological advances in acupoint thread embedding treatment: Effects on NIHSS score, Serum SIRT1, HIF-1α, and macrophage efferocytosis in stroke patients

BackgroundAcupoint thread embedding treatment (ATET) is a traditional therapeutic approach used in stroke rehabilitation.ObjectiveTo explore the application of ATET in combination with modern medical technology, examining its effects on neurological function and key serum biomarkers in stroke patients.MethodsA total of 108 stroke patients were randomly assigned to ATE treatment group (n = 52) and Control Group (n = 56). Various parameters including baseline characteristics, levels of inflammatory markers, macrophage efferocytosis-related factors, the National Institutes of Health Stroke Scale (NIHSS) scores, therapeutic efficacy, and adverse events were assessed and compared between the two groups.ResultsA significant improvement in NIHSS scores was observed in the treatment group compared to the control group. Additionally, serum levels of SIRT1, HIF-1α, and macrophage efferocytosis-related factors were significantly altered, suggesting that ATET may influence biological pathways involved in stroke recovery.ConclusionThe application of ATET, supported by advanced diagnostic technologies, shows promising effects in stroke rehabilitation. This study highlights the potential for integrating traditional therapies with modern medicine to improve clinical outcomes in stroke patients.

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Publication Details

Journal
Technology and Health Care
Published
2025-08-05
DOI
https://doi.org/10.1177/09287329251363433
Primary Topic
Healthcare and Venom Research
Type
article
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article

Technological advances in acupoint thread embedding treatment: Effects on NIHSS score, Serum SIRT1, HIF-1α, and macrophage efferocytosis in stroke patients

Jie Shi, Hailong Pang, Qingbo Lv, Wenhao Huang et al.
Technology and Health Care
Healthcare and Venom Research
article

Technological advances in acupoint thread embedding treatment: Effects on NIHSS score, Serum SIRT1, HIF-1α, and macrophage efferocytosis in stroke patients

Jie Shi, Hailong Pang, Qingbo Lv, Wenhao Huang, Miaoying Hong, J Cai, Wanyi Xie, Mingyi He, Min Li, H S Zou
article en

Abstract

BackgroundAcupoint thread embedding treatment (ATET) is a traditional therapeutic approach used in stroke rehabilitation.ObjectiveTo explore the application of ATET in combination with modern medical technology, examining its effects on neurological function and key serum biomarkers in stroke patients.MethodsA total of 108 stroke patients were randomly assigned to ATE treatment group (n = 52) and Control Group (n = 56). Various parameters including baseline characteristics, levels of inflammatory markers, macrophage efferocytosis-related factors, the National Institutes of Health Stroke Scale (NIHSS) scores, therapeutic efficacy, and adverse events were assessed and compared between the two groups.ResultsA significant improvement in NIHSS scores was observed in the treatment group compared to the control group. Additionally, serum levels of SIRT1, HIF-1α, and macrophage efferocytosis-related factors were significantly altered, suggesting that ATET may influence biological pathways involved in stroke recovery.ConclusionThe application of ATET, supported by advanced diagnostic technologies, shows promising effects in stroke rehabilitation. This study highlights the potential for integrating traditional therapies with modern medicine to improve clinical outcomes in stroke patients.

Technology and Health Care
Guangzhou University of Chinese Medicine (CN), Guangdong Provincial Hospital of Traditional Chinese Medicine (CN)
Good health and well-being
Openalex Percentile: Top 78%
Healthcare and Venom Research
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Technological advances in acupoint thread embedding treatment: Effects on NIHSS score, Serum SIRT1, HIF-1α, and macrophage efferocytosis in stroke patients — Jie Shi, Hailong Pang, et al. · Technology and Health Care (2025) | TGRS Research Map | TGRS