One-year follow-up of the immunogenicity and safety of a first and second booster dose of the NVX-CoV2373 (TAK-019) vaccine in healthy Japanese adults who had previously received a primary series of COVID-19 mRNA vaccine: Final report of a phase 3 op
The two NVX-CoV2373 boosters induced durable anti-SARS-CoV-2 immune responses up to 1 year after each dose and are therefore expected to persistently protect against SARS-CoV-2 infections and severe disease outcomes in Japanese adults. No new safety concerns were identified, demonstrating the expected acceptable safety profile in healthy Japanese participants.
Authors
- Kenji Kuriyama
- Ron P. Schuring
- Mitsuhiro Mori (ORCID: https://orcid.org/0000-0002-0758-9642)
- Sho Sakui
- Kyoko Murakami (ORCID: https://orcid.org/0000-0001-9041-0043)
- Kenkichi Sugiura
Institutions
- Takeda (Switzerland) (CH)
- Takeda (Japan) (JP)
Publication Details
- Journal
- Vaccine
- Published
- 2025-08-01
- DOI
- https://doi.org/10.1016/j.vaccine.2025.127562
- Citations
- 2
- Primary Topic
- SARS-CoV-2 and COVID-19 Research
- Type
- article
- Field-Weighted Citation Impact
- 2.79