One-year follow-up of the immunogenicity and safety of a first and second booster dose of the NVX-CoV2373 (TAK-019) vaccine in healthy Japanese adults who had previously received a primary series of COVID-19 mRNA vaccine: Final report of a phase 3 op

The two NVX-CoV2373 boosters induced durable anti-SARS-CoV-2 immune responses up to 1 year after each dose and are therefore expected to persistently protect against SARS-CoV-2 infections and severe disease outcomes in Japanese adults. No new safety concerns were identified, demonstrating the expected acceptable safety profile in healthy Japanese participants.

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Publication Details

Journal
Vaccine
Published
2025-08-01
DOI
https://doi.org/10.1016/j.vaccine.2025.127562
Citations
2
Primary Topic
SARS-CoV-2 and COVID-19 Research
Type
article
Field-Weighted Citation Impact
2.79
Controls
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article

One-year follow-up of the immunogenicity and safety of a first and second booster dose of the NVX-CoV2373 (TAK-019) vaccine in healthy Japanese adults who had previously received a primary series of COVID-19 mRNA vaccine: Final report of a phase 3 op

Kenji Kuriyama, Ron P. Schuring, Mitsuhiro Mori, Sho Sakui et al.
2 citations
Vaccine
SARS-CoV-2 and COVID-19 Research
2.79
article

One-year follow-up of the immunogenicity and safety of a first and second booster dose of the NVX-CoV2373 (TAK-019) vaccine in healthy Japanese adults who had previously received a primary series of COVID-19 mRNA vaccine: Final report of a phase 3 op

Kenji Kuriyama, Ron P. Schuring, Mitsuhiro Mori, Sho Sakui, Kyoko Murakami, Kenkichi Sugiura
article en
2 citations

Abstract

The two NVX-CoV2373 boosters induced durable anti-SARS-CoV-2 immune responses up to 1 year after each dose and are therefore expected to persistently protect against SARS-CoV-2 infections and severe disease outcomes in Japanese adults. No new safety concerns were identified, demonstrating the expected acceptable safety profile in healthy Japanese participants.

VaccineVol. 62
Takeda (Switzerland) (CH), Takeda (Japan) (JP)
Good health and well-being
Openalex Percentile: Top 9%
SARS-CoV-2 and COVID-19 Research
2.79
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