Exploring 1400 Plasma Metabolites and Polycystic Ovary Syndrome: A Bidirectional Mendelian Randomization Study

Thirteen plasma metabolites were identified as protective factors for PCOS. Targeted modulation of these metabolites may improve metabolic dysfunction in patients, alleviating symptoms and enhancing quality of life. Further exploration of metabolite dynamics could advance mechanistic insights into PCOS pathogenesis and inform therapeutic development.

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Publication Details

Journal
Brain and Behavior
Published
2025-08-01
DOI
https://doi.org/10.1002/brb3.70745
Citations
1
Primary Topic
Ovarian function and disorders
Type
article
Field-Weighted Citation Impact
1.70

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article

Exploring 1400 Plasma Metabolites and Polycystic Ovary Syndrome: A Bidirectional Mendelian Randomization Study

Yanqin Huang, Xiaoli Lei, Yi Qu, X Y Liu
1 citations
Brain and Behavior
Ovarian function and disorders
1.70
article

Exploring 1400 Plasma Metabolites and Polycystic Ovary Syndrome: A Bidirectional Mendelian Randomization Study

Yanqin Huang, Xiaoli Lei, Yi Qu, X Y Liu
article en
1 citations

Abstract

Thirteen plasma metabolites were identified as protective factors for PCOS. Targeted modulation of these metabolites may improve metabolic dysfunction in patients, alleviating symptoms and enhancing quality of life. Further exploration of metabolite dynamics could advance mechanistic insights into PCOS pathogenesis and inform therapeutic development.

Brain and BehaviorVol. 15(8)
Shandong University of Traditional Chinese Medicine (CN), Taian City Central Hospital (CN), Affiliated Hospital of Shandong University of Traditional Chinese Medicine (CN)
Taishan Scholar Foundation of Shandong Province
Openalex Percentile: Top 14%
Ovarian function and disorders
1.70
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