Exploring the Causal Relationship Between Inflammatory Bowel Disease and Bell's Palsy Based on Inflammatory Proteins: A Mendelian Randomization Study
The findings indicate that IBD may be a risk factor for Bell's palsy at the genetic level. CXCL5, IL_17C, and SLAMF1 are possible co-acting pathways between Bell's palsy and inflammatory bowel disease. These findings may provide new targets for the treatment of both diseases.
Authors
- Daofeng Fan (ORCID: https://orcid.org/0000-0002-5378-9100)
- Jianhui Dai (ORCID: https://orcid.org/0000-0001-6296-2510)
- Rui Qiu (ORCID: https://orcid.org/0000-0002-3511-6164)
- Qizhou Lian (ORCID: https://orcid.org/0000-0001-8189-7160)
- Wenbao Wu (ORCID: https://orcid.org/0000-0003-1918-7779)
- Changbo Zhao
- Yinjuan Chen (ORCID: https://orcid.org/0009-0006-7426-5599)
- Binfu Que
Institutions
- Fujian Medical University (CN)
- Longyan University (CN)
- First Affiliated Hospital of Fujian Medical University (CN)
- First Teaching Hospital of Tianjin University of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Brain and Behavior
- Published
- 2025-08-01
- DOI
- https://doi.org/10.1002/brb3.70715
- Primary Topic
- Facial Nerve Paralysis Treatment and Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Natural Science Foundation of Fujian Province
- Science and Technology Project of Longyan City