The therapeutic potential of neuroglobin-overexpressing human neural stem cells in a photothrombosis model
These findings demonstrate that F3.NGB cells reduce ischemic brain damage primarily by enhancing cell proliferation, and also migrate to the injury site and undergo differentiation into neurons or astrocytes. These results suggest that F3.NGB cell-based therapy may contribute to the development of advanced regenerative strategies for the treatment of ischemic stroke.
Authors
- Jiwon Jeong (ORCID: https://orcid.org/0000-0003-3985-0021)
- Dongsun Park (ORCID: https://orcid.org/0000-0001-6042-5949)
- Yunseo Choi
- Eun‐Jung Yoon (ORCID: https://orcid.org/0000-0003-3644-6090)
- J. De An
Institutions
- Korea National University of Education (KR)
- Kangwon National University (KR)
- Kongju National University (KR)
Publication Details
- Journal
- Regenerative Therapy
- Published
- 2025-08-05
- DOI
- https://doi.org/10.1016/j.reth.2025.07.013
- Primary Topic
- Hemoglobin structure and function
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Ministry of Education
- National Research Foundation of Korea