Genetic and Environmental Contributions to Serological Biomarkers of Extracellular Matrix Remodeling in Asthma: A Twin Study
This study highlights ECM remodeling's role in asthma and airway obstruction, identifying distinct biomarker profiles. Genetic factors significantly influence ECM changes, suggesting potential genetic predispositions for ECM alterations and offering insights into asthma pathogenesis and future diagnostic and therapeutic strategies.
Authors
- Simon Francis Thomsen (ORCID: https://orcid.org/0000-0003-1575-9629)
- Kirsten Ohm Kyvik (ORCID: https://orcid.org/0000-0003-2981-0245)
- Signe Holm Nielsen (ORCID: https://orcid.org/0000-0002-4612-1014)
- Vibeke Backer (ORCID: https://orcid.org/0000-0002-7806-7219)
- Matej Andelic (ORCID: https://orcid.org/0009-0009-3096-0444)
Institutions
- University of Copenhagen (DK)
- University of Southern Denmark (DK)
- Bispebjerg Hospital (DK)
- Copenhagen University Hospital (DK)
- Rigshospitalet (DK)
- Nordic Bioscience (Denmark) (DK)
Publication Details
- Journal
- Clinical and Translational Allergy
- Published
- 2025-08-01
- DOI
- https://doi.org/10.1002/clt2.70089
- Citations
- 1
- Primary Topic
- Asthma and respiratory diseases
- Type
- article
- Field-Weighted Citation Impact
- 1.16
Funders
- Innovationsfonden