Integrated transcriptomic and metabolomic analysis of the antibacterial mechanism of Rhizoma Coptidis extract against Staphylococcus epidermidis ATCC 35984

The study provides new insights into the antibacterial and anti-biofilm mechanisms of Rhizoma Coptidis extract against S. epidermidis, highlighting its potential as a therapeutic agent for combating biofilm-associated infections.

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Publication Details

Journal
BMC Microbiology
Published
2025-08-05
DOI
https://doi.org/10.1186/s12866-025-04169-z
Citations
2
Primary Topic
Antimicrobial Peptides and Activities
Type
article
Field-Weighted Citation Impact
2.37
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article

Integrated transcriptomic and metabolomic analysis of the antibacterial mechanism of Rhizoma Coptidis extract against Staphylococcus epidermidis ATCC 35984

Li Shao, Laiji Ma, Lu Wang, Huan Zhang et al.
2 citations
BMC Microbiology
Antimicrobial Peptides and Activities
2.37
article

Integrated transcriptomic and metabolomic analysis of the antibacterial mechanism of Rhizoma Coptidis extract against Staphylococcus epidermidis ATCC 35984

Li Shao, Laiji Ma, Lu Wang, Huan Zhang, Shuai Yang, Xing Yan
article en
2 citations

Abstract

The study provides new insights into the antibacterial and anti-biofilm mechanisms of Rhizoma Coptidis extract against S. epidermidis, highlighting its potential as a therapeutic agent for combating biofilm-associated infections.

BMC MicrobiologyVol. 25(1)
Shandong Academy of Pharmaceutical Sciences (CN), Shanghai Institute of Technology (CN)
Good health and well-being
Openalex Percentile: Top 10%
Antimicrobial Peptides and Activities
2.37
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