Study of Heat Transfer Simulation Method for Magnetic Hyperthermia Considering Heat Generation Characteristics of Thermo‐Sensitive Magnetic Particle

The purpose of this paper is to establish a heat transfer simulation method for magnetic hyperthermia that incorporates the heat generation characteristics of low curie point thermo‐sensitive magnetic particles and their relative position to a Drive coil that applies the magnetic field. We developed a method for estimating heat generation based on the magnetic permeability of the thermo‐sensitive magnetic particles and the magnetic field distribution of the Drive coil. Additionally, we measured the temporal change in heat generation through two physical experiments that varied the agglomeration density and distribution shape of the thermo‐sensitive magnetic particles. The results demonstrated that the proposed simulation method could replicate the experimental results with an average error of 0.7% and 1.3%, respectively. Furthermore, physical experiments and heat transfer simulations show that the maximum heat generation of the thermo‐sensitive magnetic particles increases linearly with increasing agglomeration density and with increasing base area of the distribution shape. © 2025 The Author(s). IEEJ Transactions on Electrical and Electronic Engineering published by Institute of Electrical Engineers of Japan and Wiley Periodicals LLC.