Corticosteroid insensitivity in asthma associated with obstructive sleep apnoea: Role of oxidative stress and histone acetylation

OSA is associated with oxidative stress, reduced HDAC2, and corticosteroid insensitivity in asthma. Antioxidants may help restore corticosteroid efficacy.

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Publication Details

Journal
British Journal of Pharmacology
Published
2025-08-04
DOI
https://doi.org/10.1111/bph.70157
Citations
1
Primary Topic
Asthma and respiratory diseases
Type
article
Field-Weighted Citation Impact
1.16
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article

Corticosteroid insensitivity in asthma associated with obstructive sleep apnoea: Role of oxidative stress and histone acetylation

Yu‐Lun Lo, Tzu‐Ting Huang, Chun‐Yu Lo, Ning‐Hung Chen et al.
1 citations
British Journal of Pharmacology
Asthma and respiratory diseases
1.16
article

Corticosteroid insensitivity in asthma associated with obstructive sleep apnoea: Role of oxidative stress and histone acetylation

Yu‐Lun Lo, Tzu‐Ting Huang, Chun‐Yu Lo, Ning‐Hung Chen, Ting‐Yu Lin, Li‐Pang Chuang, Shu‐Min Lin, Shih‐Wei Lin, Jung‐Ru He, Kian Fan Chung, Chih‐Chen Heh, Hao Luo, Chun‐Yu Lin, Po‐Jui Chang, Tsai‐Yu Wang, Chun‐Hua Wang, Horng‐Chyuan Lin
article en
1 citations

Abstract

OSA is associated with oxidative stress, reduced HDAC2, and corticosteroid insensitivity in asthma. Antioxidants may help restore corticosteroid efficacy.

British Journal of PharmacologyVol. 182(23)
Chang Gung University (TW), Harefield Hospital (GB), Chang Gung Memorial Hospital (TW), Taoyuan Chang Gung Memorial Hospital (TW), Linkou Chang Gung Memorial Hospital (TW)
Openalex Percentile: Top 19%
Asthma and respiratory diseases
1.16
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Corticosteroid insensitivity in asthma associated with obstructive sleep apnoea: Role of oxidative stress and histone acetylation — Yu‐Lun Lo, Tzu‐Ting Huang, et al. · British Journal of Pharmacology (2025) | TGRS Research Map | TGRS