Role of diabetes-related inflammation in pancreatic cancer evaluated by aptamer-based detection of circulating tumor cells in a streptozotocin-induced Panc02-transplanted murine model
In STZ-induced murine models, both hyperglycemia and elevated inflammatory markers were observed. Within this diabetes-associated inflammatory microenvironment, pancreatic cancer cells demonstrated increased proliferation and metastasis, as verified by aptasensor-based CTC detection.
Authors
- Ho‐Seong Han (ORCID: https://orcid.org/0000-0001-9659-1260)
- Yeshong Park (ORCID: https://orcid.org/0000-0002-0638-3001)
- Yoo‐Seok Yoon (ORCID: https://orcid.org/0000-0001-7621-8557)
- Sang-Tae Kim
- Yumi Kim (ORCID: https://orcid.org/0000-0001-6636-5182)
Institutions
- Seoul National University Bundang Hospital (KR)
Publication Details
- Journal
- Annals of Hepato-Biliary-Pancreatic Surgery
- Published
- 2025-08-05
- DOI
- https://doi.org/10.14701/ahbps.25-120
- Citations
- 1
- Primary Topic
- Pancreatic and Hepatic Oncology Research
- Type
- article
- Field-Weighted Citation Impact
- 1.05
Funders
- Seoul National University Bundang Hospital