Dissolving microneedle patches for transdermal delivery of paroxetine: <i>in-vitro, ex-vivo</i> studies and its PBPK modeling
The prepared MNPs were stable and can deliver PRX-HCl sufficiently across skin barrier with enhanced bioavailability compared to oral administration at similar doses and thus be a better alternative to already available delivery systems for PRX-HCl.
Authors
- Muhammad Talha Saleem (ORCID: https://orcid.org/0000-0001-5989-8335)
- Asma Irshad (ORCID: https://orcid.org/0000-0002-0594-5877)
- Muhammad Harris Shoaib (ORCID: https://orcid.org/0000-0002-3639-0026)
- Farrukh Rafiq Ahmed (ORCID: https://orcid.org/0000-0002-5696-3426)
- Fahad Siddiqui (ORCID: https://orcid.org/0000-0001-9248-2796)
- Rabia Ismail Yousuf
- Muhammad Sikandar
Institutions
- University of Karachi (PK)
Publication Details
- Journal
- Therapeutic Delivery
- Published
- 2025-08-03
- DOI
- https://doi.org/10.1080/20415990.2025.2542721
- Citations
- 1
- Primary Topic
- Advancements in Transdermal Drug Delivery
- Type
- article
- Field-Weighted Citation Impact
- 0.79