Association of maternal asthma with congenital heart defects in offspring
Maternal asthma and allergic tendency are associated with a modestly increased risk of CHD in offspring, particularly VSD. Nonallergic asthma was also linked to CHD, especially right-sided defects. These findings suggest that maternal allergic inflammation may have teratogenic effects during fetal cardiac development.
Authors
- Turkka Kirjavainen (ORCID: https://orcid.org/0000-0002-0043-5093)
- Mika Gissler (ORCID: https://orcid.org/0000-0001-8254-7525)
- Mari Kemppainen (ORCID: https://orcid.org/0000-0002-5680-7394)
- Emmi Helle (ORCID: https://orcid.org/0000-0001-8993-2194)
Institutions
- National Bureau of Investigation (FI)
- University of Helsinki (FI)
- Helsinki Institute of Physics (FI)
- Helsinki University Hospital (FI)
- Karolinska Institutet (SE)
- Finnish Institute for Health and Welfare (FI)
- Helsinki Children's Hospital (FI)
- Stockholm Health Care Services (SE)
Publication Details
- Journal
- Acta Obstetricia Et Gynecologica Scandinavica
- Published
- 2025-08-03
- DOI
- https://doi.org/10.1111/aogs.70032
- Citations
- 1
- Primary Topic
- Eosinophilic Esophagitis
- Type
- article
- Field-Weighted Citation Impact
- 2.01
Funders
- Lastentautien Tutkimussäätiö