An Enhanced CT-based Radiomics Model for Predicting the Anaplastic Lymphoma Kinase Mutation Status in Lung Adenocarcinoma

The CT-derived radiomics signature and nomogram show promise for preoperative ALK mutation prediction in lung adenocarcinoma. These tools could enhance clinical decision-making by identifying candidates for targeted therapies, though further validation is needed to optimize their application in diverse populations.

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Publication Details

Journal
Current Medical Imaging Formerly Current Medical Imaging Reviews
Published
2025-08-04
DOI
https://doi.org/10.2174/0115734056376470250718053430
Primary Topic
Radiomics and Machine Learning in Medical Imaging
Type
article
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article

An Enhanced CT-based Radiomics Model for Predicting the Anaplastic Lymphoma Kinase Mutation Status in Lung Adenocarcinoma

Lei Yang, Taijuan Zhang, Hui Ding, Zaixian Zhang et al.
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Current Medical Imaging Formerly Current Medical Imaging Reviews
Radiomics and Machine Learning in Medical Imaging
article

An Enhanced CT-based Radiomics Model for Predicting the Anaplastic Lymphoma Kinase Mutation Status in Lung Adenocarcinoma

Lei Yang, Taijuan Zhang, Hui Ding, Zaixian Zhang, Yaqiong Ge, Zhiming Li, Shunli Liu
article en

Abstract

The CT-derived radiomics signature and nomogram show promise for preoperative ALK mutation prediction in lung adenocarcinoma. These tools could enhance clinical decision-making by identifying candidates for targeted therapies, though further validation is needed to optimize their application in diverse populations.

Current Medical Imaging Formerly Current Medical Imaging ReviewsVol. 21
Qingdao University (CN), Affiliated Hospital of Qingdao University (CN), United Imaging Healthcare (China) (CN), Qingdao Women and Children's Hospital (CN)
Openalex Percentile: Top 72%
Radiomics and Machine Learning in Medical Imaging
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An Enhanced CT-based Radiomics Model for Predicting the Anaplastic Lymphoma Kinase Mutation Status in Lung Adenocarcinoma — Lei Yang, Taijuan Zhang, et al. · Current Medical Imaging Formerly Current Medical Imaging Reviews (2025) | TGRS Research Map | TGRS