Fulminant Influenza A Myocarditis in a Healthy Young Adult Salvaged With Biventricular Impella Support: A Case Report

Fulminant myocarditis is a rare but life-threatening complication of influenza A infection that can result in acute biventricular failure leading to cardiogenic shock. Here, we present the case of a young patient who developed acute bilateral heart failure secondary to influenza A and was successfully stabilized using both right and left-sided Impella devices. This case highlights the critical role of early and aggressive mechanical circulatory support (MCS) in managing fulminant myocarditis and emphasizes the utility of Impella in cases of severe cardiac dysfunction. Our patient showed a remarkable recovery, with significant improvement in ejection fraction within days of initiating MCS. Notably, a strong family history of myocarditis was present, raising the possibility of a genetic predisposition to developing fulminant myocarditis in response to viral infections. This case underscores the potential for serious and potentially fatal cardiogenic complications of a common viral illness in genetically susceptible individuals.

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Publication Details

Journal
Cureus
Published
2025-08-04
DOI
https://doi.org/10.7759/cureus.89322
Primary Topic
Viral Infections and Immunology Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Fulminant Influenza A Myocarditis in a Healthy Young Adult Salvaged With Biventricular Impella Support: A Case Report

Maheen Zaidi, Fatima Rajab, Ahmad Jalil
Cureus
Viral Infections and Immunology Research
article

Fulminant Influenza A Myocarditis in a Healthy Young Adult Salvaged With Biventricular Impella Support: A Case Report

Maheen Zaidi, Fatima Rajab, Ahmad Jalil
article en

Abstract

Fulminant myocarditis is a rare but life-threatening complication of influenza A infection that can result in acute biventricular failure leading to cardiogenic shock. Here, we present the case of a young patient who developed acute bilateral heart failure secondary to influenza A and was successfully stabilized using both right and left-sided Impella devices. This case highlights the critical role of early and aggressive mechanical circulatory support (MCS) in managing fulminant myocarditis and emphasizes the utility of Impella in cases of severe cardiac dysfunction. Our patient showed a remarkable recovery, with significant improvement in ejection fraction within days of initiating MCS. Notably, a strong family history of myocarditis was present, raising the possibility of a genetic predisposition to developing fulminant myocarditis in response to viral infections. This case underscores the potential for serious and potentially fatal cardiogenic complications of a common viral illness in genetically susceptible individuals.

CureusVol. 17(8)
King Edward Medical University (PK)
Zero hunger
Openalex Percentile: Top 69%
Viral Infections and Immunology Research
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