Characterizing immune and metabolic profiles in autism spectrum disorder through combined transcriptomics-metabonomics analysis
The parallel findings of dysregulation of metabolic and transcriptomic pathways in ASD from distinct cohorts point towards intricate commonalities that contribute to its phenotype. This multi-omics approach provides valuable insights and supports the development of precision medicine strategies. Future research should focus on longitudinal studies to explore these changes across developmental stages and environmental influences, offering a more comprehensive perspective on ASD management.
Authors
- Yuxuan Meng (ORCID: https://orcid.org/0009-0009-4287-5861)
- Xin’e Shi (ORCID: https://orcid.org/0000-0001-6036-9668)
- Peng George Wang (ORCID: https://orcid.org/0000-0003-3335-6794)
- Jinrui Jia
- Zhijie He (ORCID: https://orcid.org/0009-0000-8770-7858)
- Mingzhi Liao
- Hao Zhang
- Shan Li (ORCID: https://orcid.org/0000-0003-2577-0653)
- Yan Li (ORCID: https://orcid.org/0000-0002-3828-8340)
- Zhibo Wang (ORCID: https://orcid.org/0000-0003-0851-2062)
- Ruiqi Zhang (ORCID: https://orcid.org/0000-0003-3475-7557)
- Lijun Feng (ORCID: https://orcid.org/0000-0002-7545-3122)
- Yajun Li
- Yanheng Ding
- Zixuan Wang (ORCID: https://orcid.org/0009-0002-5308-2460)
Institutions
- North West Agriculture and Forestry University (CN)
- Northwest Women's and Children's Hospital (CN)
- Northwest A&F University (CN)
Publication Details
- Journal
- Journal of Psychiatric Research
- Published
- 2025-08-05
- DOI
- https://doi.org/10.1016/j.jpsychires.2025.07.018
- Citations
- 2
- Primary Topic
- Autism Spectrum Disorder Research
- Type
- article
- Field-Weighted Citation Impact
- 2.86