Optimisation of the extraction process of Jian Pi Qing Re Xiao Cuo Fang based on AHP-entropy weighting method
<sec> <title>目的</title> 优化健脾清热消痤方现代提取工艺参数。 </sec> <sec> <title>方法</title> 根据单因素考察，选取加水倍数、提取时间和提取次数为关键工艺参数进行正交设计，将指标成分的质量分数以及指纹图谱相似度和干膏率作为评价指标，采用层次分析法（AHP）、熵值法和AHP-熵值混合加权法确定各指标权重系数，比较单一赋权法和混合加权法，结合正交结果优选健脾清热消痤方提取工艺参数，并对其进行验证试验。 </sec> <sec> <title>结果</title> 优选提取工艺条件为加10倍水，提取30 min，提取3次。 </sec> <sec> <title>结论</title> 通过AHP-熵值混合加权法优选的健脾清热消痤方提取工艺合理可行，适用于医院制剂开发。 </sec>
Authors
- Peng Wu (ORCID: https://orcid.org/0000-0003-1157-9401)
- Yue Xie (ORCID: https://orcid.org/0000-0001-9062-6928)
- Qi Liang (ORCID: https://orcid.org/0000-0001-5598-6012)
- Zhongqiu Liu (ORCID: https://orcid.org/0000-0001-6986-9677)
- Chunlei Liu (ORCID: https://orcid.org/0000-0001-8816-4832)
- Han Yang (ORCID: https://orcid.org/0009-0000-4322-6753)
- Q. Mei
Publication Details
- Journal
- Lishizhen medicine and materia medica research
- Published
- 2025-01-01
- DOI
- https://doi.org/10.70976/j.1008-0805.szgygy-2025-0111
- Primary Topic
- Extenics and Innovation Methods
- Type
- article
- Field-Weighted Citation Impact
- 0.00