Study finds no link between prenatal antidepressant exposure and childhood depression

Adjusted analyses in a U.S. cohort study found that children exposed in utero to antidepressants were at no higher risk of onset of depression or anxiety than youths whose mothers did not use antidepressants or used the medications in the year before pregnancy. The results suggested that underlying maternal depression is a greater predictor of a childhood depressive diagnosis than antidepressant exposure.

Publication Details

Journal
The Brown University Psychopharmacology Update
Published
2025-08-04
DOI
https://doi.org/10.1002/pu.31347
Primary Topic
Maternal Mental Health During Pregnancy and Postpartum
Type
article
Field-Weighted Citation Impact
0.00
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article

Study finds no link between prenatal antidepressant exposure and childhood depression

The Brown University Psychopharmacology Update
Maternal Mental Health During Pregnancy and Postpartum
article

Study finds no link between prenatal antidepressant exposure and childhood depression

article en

Abstract

Adjusted analyses in a U.S. cohort study found that children exposed in utero to antidepressants were at no higher risk of onset of depression or anxiety than youths whose mothers did not use antidepressants or used the medications in the year before pregnancy. The results suggested that underlying maternal depression is a greater predictor of a childhood depressive diagnosis than antidepressant exposure.

The Brown University Psychopharmacology UpdateVol. 36(9)
Openalex Percentile: Top 73%
Maternal Mental Health During Pregnancy and Postpartum
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Study finds no link between prenatal antidepressant exposure and childhood depression · The Brown University Psychopharmacology Update (2025) | TGRS Research Map | TGRS