Review finds GLP‐1s have favorable psychiatric safety profile

Use of glucagon‐like peptide 1 (GLP‐1) receptor agonists in patients with diabetes and/or obesity did not increase risk of psychiatric adverse effects or worsening depressive symptoms, a systematic review and meta‐analysis has found. Use of GLP‐1s in these populations also improved several quality‐of‐life outcomes. Results of the review and meta‐analysis were published online May 14, 2025, in JAMA Psychiatry .

Publication Details

Journal
The Brown University Psychopharmacology Update
Published
2025-08-04
DOI
https://doi.org/10.1002/pu.31345
Primary Topic
Diabetes Treatment and Management
Type
article
Field-Weighted Citation Impact
0.00
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article

Review finds GLP‐1s have favorable psychiatric safety profile

The Brown University Psychopharmacology Update
Diabetes Treatment and Management
article

Review finds GLP‐1s have favorable psychiatric safety profile

article en

Abstract

Use of glucagon‐like peptide 1 (GLP‐1) receptor agonists in patients with diabetes and/or obesity did not increase risk of psychiatric adverse effects or worsening depressive symptoms, a systematic review and meta‐analysis has found. Use of GLP‐1s in these populations also improved several quality‐of‐life outcomes. Results of the review and meta‐analysis were published online May 14, 2025, in JAMA Psychiatry .

The Brown University Psychopharmacology UpdateVol. 36(9)
Openalex Percentile: Top 73%
Diabetes Treatment and Management
DOISourceOpenAlex
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Review finds GLP‐1s have favorable psychiatric safety profile · The Brown University Psychopharmacology Update (2025) | TGRS Research Map | TGRS