Single-Distance, Single-Modulation-Frequency, Multispectral Near Infrared Spectroscopy to Determine Absolute Concentrations of Tissue Chromophores
We present a novel optimization-based methodology to estimate absolute chromophore concentrations including the redox state of cytochrome-c-oxidase using single-distance, single-modulation, eight-wavelength frequency-domain near-infrared spectroscopy. This approach facilitates the reduction of device costs and depth-resolved quantifications.
Authors
- Hanli Liu (ORCID: https://orcid.org/0000-0002-0420-4284)
- Muaaz Faiyazuddin
Institutions
- The University of Texas at Arlington (US)
Publication Details
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1364/brain.2025.bw2b.5
- Primary Topic
- Spectroscopy Techniques in Biomedical and Chemical Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00