Age-dependent bone mineral density responses to gender-affirming hormone therapy in transgender individuals: a one-year prospective study
GAHT has variable effects on bone health, influenced by age and sex assigned at birth. Early initiation may favor bone accrual, especially in AMAB individuals, while AFAB individuals may require closer monitoring for site-specific bone loss during testosterone therapy.
Authors
- Alberto Ferlin (ORCID: https://orcid.org/0000-0001-5817-8141)
- Andrea Garolla (ORCID: https://orcid.org/0000-0003-4736-9051)
- Mario Virgilio Papa (ORCID: https://orcid.org/0000-0002-1579-2202)
- Anna Bertocco (ORCID: https://orcid.org/0000-0002-0652-1064)
- Giuseppe Sergi (ORCID: https://orcid.org/0000-0001-9757-856X)
- Alberto Scala (ORCID: https://orcid.org/0009-0009-1960-537X)
- Giulia Termini (ORCID: https://orcid.org/0000-0001-8544-8274)
- Chiara Ceolin (ORCID: https://orcid.org/0000-0001-5064-1672)
- Sandro Giannini (ORCID: https://orcid.org/0000-0003-0796-9749)
- Marina De Rui (ORCID: https://orcid.org/0000-0003-4966-1312)
- Gianluca Casali
- Martina Dall'Agnol
Institutions
- University of Padua (IT)
- Karolinska Institutet (SE)
Publication Details
- Journal
- Journal of Endocrinological Investigation
- Published
- 2025-08-04
- DOI
- https://doi.org/10.1007/s40618-025-02675-5
- Primary Topic
- LGBTQ Health, Identity, and Policy
- Type
- article
- Field-Weighted Citation Impact
- 0.00