Systematic network pharmacology and experimental validation reveal anti-glioma mechanisms of ganoderma lucidum via multi-target regulation
This study reveals the multi-target, multi-pathway mechanisms by which Ganoderma may exert therapeutic effects against glioma. Beta-Sitosterol is a promising active compound with significant anti-glioma potential, providing a scientific basis for the development of novel complementary therapies from traditional medicine.
Authors
- Jufen Zhang (ORCID: https://orcid.org/0000-0003-2704-6212)
- Fang Wang (ORCID: https://orcid.org/0000-0001-9986-0948)
- Lu Chen
- Xue Mei
Institutions
- People's Liberation Army 401 Hospital (CN)
- 181st Hospital of Chinese People's Liberation Army (CN)
Publication Details
- Journal
- Discover Oncology
- Published
- 2025-08-04
- DOI
- https://doi.org/10.1007/s12672-025-03280-x
- Primary Topic
- Fungal Biology and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00