Comparative performance of Kato–Katz, POC-CCA and real-time PCR in detecting Schistosoma mansoni infection at different endemicity settings in northwest Ethiopia: a cross-sectional study
The KK demonstrates low sensitivity, particularly in low-transmission settings. Both the POC-CCA test and RT-PCR show good performance for detecting S. mansoni infection. However, due to its complexity and resource requirements, RT-PCR is not feasible for routine field use. Therefore, we recommend the adoption of the POC-CCA test in Ethiopia's SCH control and elimination programs.
Authors
- Endalkachew Nibret (ORCID: https://orcid.org/0000-0002-7063-2877)
- Melaku Anegagrie
- Arancha Amor (ORCID: https://orcid.org/0000-0001-8576-9051)
- Maria Delmans Flores-Chavez (ORCID: https://orcid.org/0000-0003-2597-3100)
- Getaneh Alemu (ORCID: https://orcid.org/0000-0003-3478-4176)
- Tadesse Hailu
- Abaineh Munshea (ORCID: https://orcid.org/0000-0002-1469-2189)
Institutions
- Instituto de Salud Carlos III (ES)
- Bahir Dar University (ET)
Publication Details
- Journal
- Tropical Medicine and Health
- Published
- 2025-08-04
- DOI
- https://doi.org/10.1186/s41182-025-00777-7
- Citations
- 1
- Primary Topic
- Parasites and Host Interactions
- Type
- article
- Field-Weighted Citation Impact
- 2.05
Funders
- Bahir Dar University
- Fundación Mundo Sano
- Amhara Regional Health Bureau