A Century After Jacobson v. Massachusetts: Public Health Ethical Perspectives of Large Language Models on Vaccination

This study evaluates and compares the ethical reasoning of open-source and closed-source large language models (LLMs) in vaccination ethics, using Jacobson v. Massachusetts as a reference. It assesses the accuracy, soundness, and alignment of LLM responses with those of a human public health expert (PHE), exploring implications for public health decisions.

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Published
2025-06-06
DOI
https://doi.org/10.1109/ethics65148.2025.11098289
Primary Topic
Vaccine Coverage and Hesitancy
Type
article
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article

A Century After Jacobson v. Massachusetts: Public Health Ethical Perspectives of Large Language Models on Vaccination

Vamshi Mugu, Mahathi Kandimalla, S. Ruthvik Mugu, Kshipra Sharma
Vaccine Coverage and Hesitancy
article

A Century After Jacobson v. Massachusetts: Public Health Ethical Perspectives of Large Language Models on Vaccination

Vamshi Mugu, Mahathi Kandimalla, S. Ruthvik Mugu, Kshipra Sharma
article en

Abstract

This study evaluates and compares the ethical reasoning of open-source and closed-source large language models (LLMs) in vaccination ethics, using Jacobson v. Massachusetts as a reference. It assesses the accuracy, soundness, and alignment of LLM responses with those of a human public health expert (PHE), exploring implications for public health decisions.

Mayo Clinic (US), The University of Texas MD Anderson Cancer Center (US), Itron (United States) (US)
Openalex Percentile: Top 75%
Vaccine Coverage and Hesitancy
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