Improving System-Level Outcomes via Artificial Intelligence Decision Support in Kidney Utilization

Transplantation provides patients suffering from end-stage kidney disease a better quality of life and long-term survival. However, over 20% of deceased donor kidneys are not utilized and never transplanted. While this is sometimes medically appropriate, this also reflects missed opportunities. We are designing Artificial Intelligence decision support for the kidney offer process to support both demand at the transplant center and supply at the organ procurement organization. This includes (1) developing deep learning models, (2) evaluating the effect of explainable interfaces, (3) improving fairness in the model output, (4) identifying factors that influence adoption decisions, and (5) conducting a randomized control trial using an ecologically valid and realistic simulation platform for behavioral experiments, to estimate the impact on kidney utilization.