Variation in HIV-1 Tat and Vpr protein amino acid sequences and its association with vascular health measures in a South African cohort: an exploratory study
The variants of the Tat and Vpr amino acid sequence were associated with arterial stiffness, which may be an underlying mechanism for cardiovascular disease development in PLHIV.
Authors
- Yolandi Breet (ORCID: https://orcid.org/0000-0001-5067-8387)
- Esmé Jansen van Vuren (ORCID: https://orcid.org/0000-0002-0307-4537)
- Iolanthé M. Kruger (ORCID: https://orcid.org/0000-0002-8636-7174)
- Monray Edward Williams (ORCID: https://orcid.org/0000-0001-6698-8451)
- Adriaan Jacobs (ORCID: https://orcid.org/0000-0003-1122-8249)
Institutions
- South African Medical Research Council (ZA)
- North-West University (ZA)
Publication Details
- Journal
- Virology Journal
- Published
- 2025-08-04
- DOI
- https://doi.org/10.1186/s12985-025-02891-8
- Citations
- 1
- Primary Topic
- HIV-related health complications and treatments
- Type
- article
- Field-Weighted Citation Impact
- 2.25
Funders
- Hamilton Health Sciences
- McMaster University
- National Research Foundation
- Poliomyelitis Research Foundation
- South Africa Netherlands research Programme on Alternatives in Development
- North-West University
- Medical Research Council