Vancomycin-resistant enterococcal infections in liver transplant recipients: Clinical impact and therapeutic approaches

Vancomycin-resistant Enterococci (VRE) are an important cause of infection in liver transplant recipients and are associated with significant morbidity and mortality. Liver transplant candidates and recipients share various risk factors for VRE infections, and colonization has been shown to be associated with increased risk for infection. With limited antimicrobial options and data available for guidance, treatment can be challenging. This review discusses the epidemiology of VRE infections in patients with end-stage liver disease and after liver transplant, as well as therapeutic approaches.