PainDETECT as a Potential Tool for Personalized Medicine: Predicting Outcome One Year After Knee Arthroplasty
Patients classified presurgery as having unclear and neuropathic pain by the modified PainDETECT have considerably worse outcomes after surgery. Neuropathic pain categorized by this tool commonly has centralized pain features and is a potential predictor of ongoing postsurgical pain. Knowledge of this may aid informed decision-making with respect to surgical intervention for those with knee osteoarthritis.
Authors
- Andrew Price (ORCID: https://orcid.org/0000-0002-4258-5866)
- Amanda J. W Wall (ORCID: https://orcid.org/0000-0002-3175-664X)
- Irene Tracey (ORCID: https://orcid.org/0000-0003-4134-6115)
- M K Javaid (ORCID: https://orcid.org/0000-0001-7985-0048)
- K.M. Leyland (ORCID: https://orcid.org/0000-0001-6999-3344)
- Vishvarani Wanigasekera (ORCID: https://orcid.org/0000-0001-9922-8993)
- Anushka Soni (ORCID: https://orcid.org/0000-0002-7831-4208)
- Cyrus Cooper (ORCID: https://orcid.org/0000-0003-3510-0709)
- Nigel Arden
- Amit Kiran (ORCID: https://orcid.org/0000-0001-7887-3184)
Institutions
- Jacksonville College (US)
- Nuffield Orthopaedic Centre (GB)
- John Radcliffe Hospital (GB)
- NIHR Oxford Musculoskeletal Biomedical Research Centre (GB)
- Arthritis UK (GB)
- MRC Lifecourse Epidemiology Unit (GB)
- University of Southampton (GB)
Publication Details
- Journal
- Mayo Clinic Proceedings Innovations Quality & Outcomes
- Published
- 2025-08-04
- DOI
- https://doi.org/10.1016/j.mayocpiqo.2025.100649
- Citations
- 1
- Primary Topic
- Total Knee Arthroplasty Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 2.01
Funders
- National Institute for Health and Care Research