How did CariesCare International perform under pandemic conditions in children? A one-year, multicentre, single-group, interventional study
Introduction CariesCare International (CCI) is a practice-friendly, health outcomes-focused, patient-centred, risk-based approach to caries management designed for the practice. The unfeasibility of a randomised clinical trial and of aerosol generating procedures (AGPs) during the COVID-19 pandemic to test the caries control effectiveness of CCI shifted it to a non-AGP, reduced on-site consultation, single-interventional study.Aim This 12-month, multicentre, single-group, interventional study aimed at primarily assessing the control of caries progression of a pandemic CCI-adapted protocol in children.Methods In total, 17 centres (n≥ 20, 3-8-year-old children/centre) were included. Trained examiners assessed (baseline: T0; one-year follow-up: T1y): CCI caries risk; oral health-related behaviours; decayed, missing and filled teeth (primary, permanent) with the epidemiological merged International Caries Detection and Assessment System (severity, activity); dental sepsis; and toothache. Trained practitioners performed one-year CCI-adapted personalised care. Dental care process acceptance was assessed in parents and dentists.Results A total of 16 centres finished the study (n = 337, 78.6%; mean age: 5.5 ± 1.6 years). There was a T0-T1y decrease in the mean number of combined primary and permanent tooth surfaces with caries lesions (8.4 ± 9.7 to 6.2 ± 7.6), with most children showing control of caries progression (75.1%), high caries risk (86.6%) and non-adequate oral-health behaviour (72.7%) (p <0.05). CCI acceptance was very high in parents and high/very high in dentists.Discussion The limitations given by the pandemic challenges, the single-interventional study design, and the non-AGP and reduced in-office-consultation adaptations, might as well highlight the shown caries progression control, feasibility and acceptance of CCI.Conclusion The one-year implementation of CCI showed control of caries progression and of risk and high acceptance among parents and dentists.
Authors
- Gail Douglas (ORCID: https://orcid.org/0000-0002-0531-3909)
- Diana Zelada (ORCID: https://orcid.org/0000-0002-7636-7971)
- Aldo Squassi (ORCID: https://orcid.org/0000-0001-7687-5805)
- Nigel Pitts (ORCID: https://orcid.org/0000-0001-6184-4213)
- Andréa Ferreira Zandoná (ORCID: https://orcid.org/0000-0003-0237-9416)
- Jesús R. Osorio
- Rita Villena (ORCID: https://orcid.org/0000-0003-4705-3233)
- Mariana Minatel Braga (ORCID: https://orcid.org/0000-0002-4469-6500)
- Ana Sorazabal (ORCID: https://orcid.org/0000-0003-3308-9120)
- Edgar O. Beltrán (ORCID: https://orcid.org/0000-0002-9044-2309)
- E. Angeles Martínez‐Mier (ORCID: https://orcid.org/0000-0002-5389-0209)
- Laura Hermida Bruno (ORCID: https://orcid.org/0000-0001-7708-5186)
- Ángela Sarrazola
- Natalia Fortich Mesa (ORCID: https://orcid.org/0000-0003-2929-0278)
- Michèle Muller‐Bolla (ORCID: https://orcid.org/0000-0003-2811-5339)
- Andrea Cortés (ORCID: https://orcid.org/0000-0001-6472-8330)
- Olga Lucía Cifuentes
- Ninoska Abreu‐Placeres (ORCID: https://orcid.org/0000-0003-1742-8102)
- Chris Deery (ORCID: https://orcid.org/0000-0001-7526-7736)
- Elody Aïem (ORCID: https://orcid.org/0000-0003-1306-783X)
- Ketty Ramos
- Irina Kuzmina
- Johanna Sanjuán
- José Ignacio Llamas
- Stefanía Martignon (ORCID: https://orcid.org/0000-0002-6505-8356)
- Juan Sebastián Lara
- Beatriz Echeverri
- María P. Cerezo
- Cristina Areias (ORCID: https://orcid.org/0000-0002-0015-2587)
- Nathaly Chavarría
- Paulo Melo (ORCID: https://orcid.org/0000-0003-3590-4926)
- Tim Newton (ORCID: https://orcid.org/0000-0003-4082-6942)
- Fabiana Carletto-Körber (ORCID: https://orcid.org/0000-0003-0641-4725)
- Angie Sanabria (ORCID: https://orcid.org/0000-0001-7977-2166)
- Magdalena San‐Martín (ORCID: https://orcid.org/0000-0002-1659-4582)
- Laura Marcela Carreño
- Adriana Conrado
- Jennifer A. Oña
- Daria Said
- Paula Yunes-Fragoso
- Alejandra Rubi Tello
- Sandra Caceres‐Matta
- Ana Clara Falabello de Luca
Institutions
- Tufts University (US)
- Moscow State University of Medicine and Dentistry (RU)
- University of Cartagena (CO)
- Universidad Nacional de Córdoba (AR)
- Universidade de São Paulo (BR)
- Universidade do Porto (PT)
- King's College London (GB)
- Universidad El Bosque (CO)
- Universidad de San Martín de Porres (PE)
- Universidad de Buenos Aires (AR)
- Universidad Iberoamericana (DO)
- Universidad Autonoma de Manizales (CO)
- Universidad Católica del Uruguay (UY)
- Corporación Universitaria Rafael Nuñez (CO)
- Institución Universitaria Colegios de Colombia (CO)
- Universidad Cooperativa de Colombia (CO)
- Leeds Dental Hospital (GB)
- The Ohio State University (US)
- Indiana University – Purdue University Indianapolis (US)
- University of Sheffield (GB)
Publication Details
- Journal
- BDJ
- Published
- 2025-08-04
- DOI
- https://doi.org/10.1038/s41415-025-8640-4
- Primary Topic
- Dental Research and COVID-19
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- International Association for Dental Research
- University of Bern
- Università degli Studi di Cagliari
- Universidad El Bosque
- King's College London