Clinical Outcomes in Patients With Quadricuspid vs Bicuspid Aortic Valve
In this large, retrospective cohort study, both QAV and BAV were associated with a high risk of aortic valve intervention. Individuals with QAV had a greater risk of HFH, while those with BAV had higher incidence of IE and aortic surgery. Despite the substantial morbidity burden, survival in both groups was similar to that in the general population.
Authors
- Christopher Tze‐Wei Tsang (ORCID: https://orcid.org/0000-0003-3394-6604)
- Yap‐Hang Chan (ORCID: https://orcid.org/0000-0001-5384-8468)
- Haochen Xuan (ORCID: https://orcid.org/0000-0002-2017-9285)
- Victoria Delgado (ORCID: https://orcid.org/0000-0002-9841-2737)
- Wenhao Zhu (ORCID: https://orcid.org/0000-0001-9446-791X)
- Zhiyuan Xia (ORCID: https://orcid.org/0009-0009-3484-079X)
- Q W Ren (ORCID: https://orcid.org/0000-0003-0712-9299)
- Gejun Zhang (ORCID: https://orcid.org/0009-0005-3155-6057)
- Tai‐Leung Chan
- Alan C. Yeung (ORCID: https://orcid.org/0000-0001-5226-3695)
- Jingnan Zhang (ORCID: https://orcid.org/0000-0002-4865-5212)
- Wenli Gu (ORCID: https://orcid.org/0000-0001-7162-6017)
- Fang Fang (ORCID: https://orcid.org/0000-0002-4023-2928)
- Ran Guo (ORCID: https://orcid.org/0000-0002-9424-8140)
- Jiayi Huang (ORCID: https://orcid.org/0000-0002-5153-506X)
- Xiaxia Pan
- Kai‐Hang Yiu
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Queen Mary Hospital (CN)
- Stanford Medicine (US)
- University of Hong Kong - Shenzhen Hospital (CN)
- Hospital Universitari Germans Trias i Pujol (ES)
- Fu Wai Hospital (CN)
- University of Hong Kong (HK)
Publication Details
- Journal
- JAMA Network Open
- Published
- 2025-08-04
- DOI
- https://doi.org/10.1001/jamanetworkopen.2025.24915
- Citations
- 1
- Primary Topic
- Aortic Disease and Treatment Approaches
- Type
- article
- Field-Weighted Citation Impact
- 1.52