Comparison of End-tidal Sevoflurane Concentration Required for Optimal Depth of Anesthesia during Opioid-free General Anesthesia Using Intravenous Lignocaine versus Morphine

Lignocaine-based OFA required a significantly higher end-tidal sevoflurane to maintain sufficient anesthetic depth compared to morphine-based anesthesia. In addition, sevoflurane use, intraoperative hypertension, and the need for supplemental analgesics were notably greater in the OFA group.

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Publication Details

Journal
Annals of African Medicine
Published
2025-08-04
DOI
https://doi.org/10.4103/aam.aam_167_25
Primary Topic
Anesthesia and Sedative Agents
Type
article
Field-Weighted Citation Impact
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article

Comparison of End-tidal Sevoflurane Concentration Required for Optimal Depth of Anesthesia during Opioid-free General Anesthesia Using Intravenous Lignocaine versus Morphine

Gayathri Sreekumar, Jerry Paul, M Manikandan, Sunil Rajan et al.
Annals of African Medicine
Anesthesia and Sedative Agents
article

Comparison of End-tidal Sevoflurane Concentration Required for Optimal Depth of Anesthesia during Opioid-free General Anesthesia Using Intravenous Lignocaine versus Morphine

Gayathri Sreekumar, Jerry Paul, M Manikandan, Sunil Rajan, Roniya Ann Roy, Fazil Haleel
article en

Abstract

Lignocaine-based OFA required a significantly higher end-tidal sevoflurane to maintain sufficient anesthetic depth compared to morphine-based anesthesia. In addition, sevoflurane use, intraoperative hypertension, and the need for supplemental analgesics were notably greater in the OFA group.

Annals of African Medicine
Amrita Institute of Medical Sciences and Research Centre (IN)
Openalex Percentile: Top 69%
Anesthesia and Sedative Agents
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