Prostaglandin E2 as a Mechanistic Biomarker of Chronic Pancreatitis

While PGE2 is detectable in pancreas fluid, these data suggest that it may not be sensitive enough to distinguish between AP/RAP and CP. However, MMPs may distinguish between stages of pancreatitis and require further testing as potential diagnostic biomarkers.

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Publication Details

Journal
Clinical and Translational Gastroenterology
Published
2025-08-04
DOI
https://doi.org/10.14309/ctg.0000000000000897
Primary Topic
Pancreatitis Pathology and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Prostaglandin E2 as a Mechanistic Biomarker of Chronic Pancreatitis

Santhi Swaroop Vege, Phil A. Hart, Darwin L. Conwell, Dhiraj Yadav et al.
Clinical and Translational Gastroenterology
Pancreatitis Pathology and Treatment
article

Prostaglandin E2 as a Mechanistic Biomarker of Chronic Pancreatitis

Santhi Swaroop Vege, Phil A. Hart, Darwin L. Conwell, Dhiraj Yadav, Evan L. Fogel, Mark Topazian, Samuel Han, Walter G. Park, Jami L. Saloman, Bahiyyah Jefferson, Liang Li, William E. Fisher
article en

Abstract

While PGE2 is detectable in pancreas fluid, these data suggest that it may not be sensitive enough to distinguish between AP/RAP and CP. However, MMPs may distinguish between stages of pancreatitis and require further testing as potential diagnostic biomarkers.

Clinical and Translational GastroenterologyVol. 16(10)
Mayo Clinic (US), The University of Texas MD Anderson Cancer Center (US), University of Kentucky (US), University of Pittsburgh (US), Baylor College of Medicine (US), University of Washington (US), WinnMed (US), The Ohio State University Wexner Medical Center (US), Pain Management Institute (US), Mayo Clinic in Arizona (US), Indiana University – Purdue University Indianapolis (US), Stanford University (US)
Good health and well-being
Openalex Percentile: Top 68%
Pancreatitis Pathology and Treatment
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