Component characterization of Smilax glabra Roxb., and its inhibitory activity against Helicobacter pylori through targeted suppression of its secreted urease
These results indicated that SGR could prominently inhibit <i>H. pylori</i> growth through targeted suppression of its secreted urease. This investigation provides substantial experimental evidence supporting the consideration of SGR as a safe and promising natural treatment for <i>H. pylori</i>-associated gastrointestinal diseases.
Authors
- Xiaoyan He (ORCID: https://orcid.org/0000-0002-2086-563X)
- Cailan Li (ORCID: https://orcid.org/0000-0001-6630-2587)
- Qiang Lü (ORCID: https://orcid.org/0000-0001-6796-9375)
- Yiqing Zhou (ORCID: https://orcid.org/0000-0002-4553-5207)
- Fan Yang (ORCID: https://orcid.org/0000-0002-2442-7098)
- Xia Wen
- Ying Tang (ORCID: https://orcid.org/0000-0002-2027-5955)
- Rong Tang (ORCID: https://orcid.org/0000-0001-7468-8424)
Institutions
- Zunyi Medical University (CN)
Publication Details
- Journal
- Frontiers in Cellular and Infection Microbiology
- Published
- 2025-07-25
- DOI
- https://doi.org/10.3389/fcimb.2025.1617330
- Primary Topic
- Helicobacter pylori-related gastroenterology studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Department of Education of Guangdong Province