A comprehensive bioinformatics analysis of pathways and biomarkers shared between type 2 diabetes mellitus and chronic obstructive pulmonary disease

The T-cell pathway may be involved in the pathogenesis of T2DM and COPD, and SUMF2 may be a potential diagnostic marker, and its high expression in T-cell subsets suggests a possible role in the immunomodulatory mechanisms underlying the two diseases.

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Publication Details

Journal
Frontiers in Immunology
Published
2025-07-25
DOI
https://doi.org/10.3389/fimmu.2025.1536551
Primary Topic
Atherosclerosis and Cardiovascular Diseases
Type
article
Field-Weighted Citation Impact
0.00

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article

A comprehensive bioinformatics analysis of pathways and biomarkers shared between type 2 diabetes mellitus and chronic obstructive pulmonary disease

Min Jiang, Dan Xu, Jianbing Ding, Duan Xiao-mei et al.
Frontiers in Immunology
Atherosclerosis and Cardiovascular Diseases
article

A comprehensive bioinformatics analysis of pathways and biomarkers shared between type 2 diabetes mellitus and chronic obstructive pulmonary disease

Min Jiang, Dan Xu, Jianbing Ding, Duan Xiao-mei, Fengsen Li, Tingting Hu, Jing Wang, Zheng Li, Li Ma, Jiale Gao, Jing Jing
article en

Abstract

The T-cell pathway may be involved in the pathogenesis of T2DM and COPD, and SUMF2 may be a potential diagnostic marker, and its high expression in T-cell subsets suggests a possible role in the immunomodulatory mechanisms underlying the two diseases.

Frontiers in ImmunologyVol. 16
Xinjiang Medical University (CN)
National Natural Science Foundation of China, Natural Science Foundation of Xinjiang
No poverty
Openalex Percentile: Top 79%
Atherosclerosis and Cardiovascular Diseases
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