A clinical study on ozone autohemotherapy for the treatment of acute ischemic stroke
It suggests that ozone may improve oxidative stress by regulating HIF-1 and Nrf-2, reduce the oxidative stress response and inflammatory damage caused by ischemia of neuronal cells in acute cerebral infarction, thereby improving neurological function and prognosis. The treatment method is safe in the short term. Long-term safety requires further research.
Authors
- Heyun Cheng
- Zhenkun Zhuang (ORCID: https://orcid.org/0009-0001-5258-9203)
- Xiaozhen Zhao (ORCID: https://orcid.org/0000-0002-9733-057X)
- Rui Lu (ORCID: https://orcid.org/0000-0003-0995-7880)
- Juan Du (ORCID: https://orcid.org/0000-0002-0068-3644)
Institutions
- Fifth Affiliated Hospital of Zhengzhou University (CN)
Publication Details
- Journal
- Frontiers in Medicine
- Published
- 2025-07-25
- DOI
- https://doi.org/10.3389/fmed.2025.1595568
- Citations
- 3
- Primary Topic
- Medical and Biological Ozone Research
- Type
- article
- Field-Weighted Citation Impact
- 4.18