Impact of polygenic risk score (PRS) for coronary artery disease on physician decision-making and patient care.
These findings highlight the potential of PRS in enhancing risk communication and clinical decision-making, primarily by reinforcing patient awareness rather than directly by altering pharmacologic management. Further research is needed to optimize PRS implementation and assess its long-term clinical impact.
Authors
- Georgios Ntritsos
- Gil Chernin (ORCID: https://orcid.org/0000-0001-7514-156X)
- Michael Y. Chen (ORCID: https://orcid.org/0000-0001-8294-6876)
- Arnold Pallay
- Nir Gamliel
- Efi Kessous
- Eran Feldhay
Institutions
- Open University of Israel (IL)
- University of Ioannina (GR)
- Hebrew University of Jerusalem (IL)
- Atlantic Health System (US)
Publication Details
- Journal
- PubMed
- Published
- 2025-01-01
- DOI
- https://doi.org/10.3389/fgene.2025.1625822
- Primary Topic
- Health Systems, Economic Evaluations, Quality of Life
- Type
- article
- Field-Weighted Citation Impact
- 0.00