Individualized supplement of water-soluble vitamins: the influence of inflammation and renal function on circulating concentrations in critically digestive disease patients
Water-soluble vitamin levels were associated with inflammation and renal function. For high inflammation, vitamin C and B9 doses may need to exceed standard levels. In renal impairment, avoid indiscriminate B2, B5, and B6 use; if needed, use alternate-day dosing or lower doses.
Authors
- Hailong Cao (ORCID: https://orcid.org/0000-0002-0147-7826)
- Wang Ying (ORCID: https://orcid.org/0000-0003-3020-5317)
- Qi Chen (ORCID: https://orcid.org/0000-0002-5289-4910)
- Jingjing Wang (ORCID: https://orcid.org/0000-0003-2347-7824)
- Jing Yan (ORCID: https://orcid.org/0000-0003-3535-1030)
- Yumei Qi
- Xiaoxiao Tian
- Gaofu Li
- Linlin Shi
Institutions
- Tianjin Medical University General Hospital (CN)
- Tianjin Third Central Hospital (CN)
- Tianjin Infectious Diseases Hospital (CN)
- Xi'an Medical University (CN)
- Tianjin Medical University (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-07-25
- DOI
- https://doi.org/10.3389/fimmu.2025.1583568
- Primary Topic
- Vitamin C and Antioxidants Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00