Case Report: Undifferentiated embryonic sarcoma of an adult liver

Undifferentiated embryonal sarcoma of the liver is a malignant mesenchymal tumor of the liver that predominantly affects children, with exceedingly rare occurrence in adults, and is associated with a poor prognosis. We present a case of undifferentiated embryonal sarcoma of the liver in a previously healthy 45-year-old man admitted to our hospital due to fever. Magnetic resonance imaging revealed a cystic-solid mass in the right lobe of the liver, measuring approximately 15 * 13 * 13 cm in size. Imaging diagnosis raised a suspicion of biliary cystadenocarcinoma with hemorrhage. A hepatic resection was successfully performed, and the histologic diagnosis was undifferentiated embryonal sarcoma of the liver. The patient received a chemotherapy regimen of ifosfamide combined with epirubicin after surgery, and no recurrence was observed after 6 months of follow-up. We herein review the clinical, radiologic, and pathologic features of this rare tumor.

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Publication Details

Journal
Frontiers in Oncology
Published
2025-07-25
DOI
https://doi.org/10.3389/fonc.2025.1599953
Citations
1
Primary Topic
Sarcoma Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
1.52
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article

Case Report: Undifferentiated embryonic sarcoma of an adult liver

Liang Bai, Xiujun Li, Lidao Bao, Shengyong Li
1 citations
Frontiers in Oncology
Sarcoma Diagnosis and Treatment
1.52
article

Case Report: Undifferentiated embryonic sarcoma of an adult liver

Liang Bai, Xiujun Li, Lidao Bao, Shengyong Li
article en
1 citations

Abstract

Undifferentiated embryonal sarcoma of the liver is a malignant mesenchymal tumor of the liver that predominantly affects children, with exceedingly rare occurrence in adults, and is associated with a poor prognosis. We present a case of undifferentiated embryonal sarcoma of the liver in a previously healthy 45-year-old man admitted to our hospital due to fever. Magnetic resonance imaging revealed a cystic-solid mass in the right lobe of the liver, measuring approximately 15 * 13 * 13 cm in size. Imaging diagnosis raised a suspicion of biliary cystadenocarcinoma with hemorrhage. A hepatic resection was successfully performed, and the histologic diagnosis was undifferentiated embryonal sarcoma of the liver. The patient received a chemotherapy regimen of ifosfamide combined with epirubicin after surgery, and no recurrence was observed after 6 months of follow-up. We herein review the clinical, radiologic, and pathologic features of this rare tumor.

Frontiers in OncologyVol. 15
Weihai Municipal Hospital (CN)
Good health and well-being, No poverty
Openalex Percentile: Top 16%
Sarcoma Diagnosis and Treatment
1.52
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