Growth-promoting hormonal alterations in pregnant women living with HIV receiving dolutegravir-based antiretroviral treatment are associated with lower infant 1-year weight z-scores
Associations between maternal growth-promoting hormones and infant weight at 1 year of life differ significantly by maternal HIV status, reflecting potential perturbations in the maternal-fetal-infant growth axis among pregnant women with HIV. Additional research is needed to identify mechanisms and possible interventions.
Authors
- Caroline Dunk (ORCID: https://orcid.org/0000-0002-4146-099X)
- Samuel W. Kgole (ORCID: https://orcid.org/0000-0001-7078-9041)
- Lena Serghides (ORCID: https://orcid.org/0000-0002-2817-6134)
- Gosego Masasa
- Jennifer Jao
- Mitchell E. Geffner (ORCID: https://orcid.org/0000-0002-0384-3287)
- Joseph Makhema (ORCID: https://orcid.org/0000-0003-0017-2438)
- Elaine J. Abrams (ORCID: https://orcid.org/0000-0001-7938-8981)
- Kathleen M. Powis (ORCID: https://orcid.org/0000-0002-4478-4471)
- Sikhulile M. Moyo (ORCID: https://orcid.org/0000-0003-3821-4592)
- Justine Legbedze
- Terence Mohammed
- Keolebogile N. Mmasa
Institutions
- Northwestern University (US)
- University Health Network (CA)
- Children's Hospital of Los Angeles (US)
- Harvard University (US)
- University of Toronto (CA)
- County Durham and Darlington NHS Foundation Trust (GB)
- Darlington Memorial Hospital (GB)
- Toronto General Hospital (CA)
- Massachusetts General Hospital (US)
- Lurie Children's Hospital (US)
- Botswana Harvard AIDS Institute Partnership (BW)
- Columbia University (US)
Publication Details
- Journal
- Frontiers in Pediatrics
- Published
- 2025-07-25
- DOI
- https://doi.org/10.3389/fped.2025.1559877
- Citations
- 1
- Primary Topic
- Birth, Development, and Health
- Type
- article
- Field-Weighted Citation Impact
- 3.49
Funders
- Canadian Institutes of Health Research
- National Institute of Diabetes and Digestive and Kidney Diseases