Comparison of Fractionated Dose Versus Bolus Dose of Hyperbaric Bupivacaine Injection in Spinal Anesthesia: Hemodynamic Stability in Elderly Patients Undergoing Lower Limb Surgeries
Fractionated dosing of hyperbaric bupivacaine in SA demonstrated improved hemodynamic stability at specific time points and reduced vasopressor requirements in elderly patients. However, due to limited power and isolated significance, further large-scale, blinded studies are needed to confirm the clinical relevance of fractionated dosing in elderly patients.
Authors
- Neha Dubey (ORCID: https://orcid.org/0000-0001-5798-968X)
- Shalini Sahu
- Shailesh Mishra (ORCID: https://orcid.org/0009-0003-7330-1912)
- Akash Verma (ORCID: https://orcid.org/0000-0002-7000-8708)
Institutions
- College of Medical Sciences (NP)
- Government Medical College (IN)
Publication Details
- Journal
- Cureus
- Published
- 2025-07-25
- DOI
- https://doi.org/10.7759/cureus.88714
- Primary Topic
- Anesthesia and Pain Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00