Effect of a Probiotic Combination on Clinical and Microbiological Oral Parameters in Head and Neck Cancer Patients: A Randomised Clinical Trial

Daily supplementation with a probiotic combination may serve as a practical and well-tolerated adjunctive measure in clinical settings to improve salivary function and reduce key oral pathogens, particularly <i>Fusobacterium nucleatum</i>, in patients undergoing or recovering from radiotherapy for head and neck cancer. These findings support its potential integration into routine supportive care protocols to mitigate xerostomia and oral dysbiosis in this population.

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Publication Details

Journal
Cancers
Published
2025-07-25
DOI
https://doi.org/10.3390/cancers17152459
Citations
2
Primary Topic
Salivary Gland Disorders and Functions
Type
article
Field-Weighted Citation Impact
2.33
Controls
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article

Effect of a Probiotic Combination on Clinical and Microbiological Oral Parameters in Head and Neck Cancer Patients: A Randomised Clinical Trial

Enric Jané Salas, Felipe Aguilera-Muñoz, Teresa Vinuesa, Alicia Lozano Borbalas et al.
2 citations
Cancers
Salivary Gland Disorders and Functions
2.33
article

Effect of a Probiotic Combination on Clinical and Microbiological Oral Parameters in Head and Neck Cancer Patients: A Randomised Clinical Trial

Enric Jané Salas, Felipe Aguilera-Muñoz, Teresa Vinuesa, Alicia Lozano Borbalas, Tanya Pereira Riveros
article en
2 citations

Abstract

Daily supplementation with a probiotic combination may serve as a practical and well-tolerated adjunctive measure in clinical settings to improve salivary function and reduce key oral pathogens, particularly <i>Fusobacterium nucleatum</i>, in patients undergoing or recovering from radiotherapy for head and neck cancer. These findings support its potential integration into routine supportive care protocols to mitigate xerostomia and oral dysbiosis in this population.

CancersVol. 17(15)
Austral University of Chile (CL), Ajuntament de L’Hospitalet (ES), Institut Català d'Oncologia (ES), Universitat de Barcelona (ES)
Good health and well-being
Openalex Percentile: Top 11%
Salivary Gland Disorders and Functions
2.33
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Effect of a Probiotic Combination on Clinical and Microbiological Oral Parameters in Head and Neck Cancer Patients: A Randomised Clinical Trial — Enric Jané Salas, Felipe Aguilera-Muñoz, et al. · Cancers (2025) | TGRS Research Map | TGRS